The Niners, fresh off an impressive upset win over the L.A. Rams, head to Florida to take on the 2-7 Jaguars. A win today would take the Niners to .500, and back in with a shout of a Wildcard berth.

Deebo Samuel has been one of the surprise studs of the season, posting over 90 yards receiving in 6 of his 9 games this season. The Jaguars rank 25th in the NFL in pass yards against per game, giving Deebo Samuel the perfect opportunity to add to his already impressive season.

Spread: Niners -6.5

Total: 45.5

Game Prediction: Niners 31-17 Jaguars

Best Bet: Deebo Samuel over 75.5 receiving yards @ 10/11 with Bet365. [1]

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