All NFC West battle between the playoff-chasing Niners and the underperforming Seahawks.

San Francisco will be without Deebo Samuel for this matchup, and that’s a huge loss when you consider how vital Deebo has been to the success of the Niners this year. Brandon Aiyuk will be tasked with replacing the production of the injured playmaker and with at least 85 receiving yards in three of his last four games I think he’s more than capable of leading an offense, especially against a Seahawks defense that ranks second-last in passing yards allowed per game.

Spread: Niners -3.0

Total: 45.0

Game Prediction: Niners 30-21 Seahawks

Best Bet: Niners +6.5 points & Brandon Aiyuk over 60.5 receiving yards @ 11/8 with Bet365 Bet Builder. [0.5]

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